Semiaquatic mammals might be intermediate hosts to spread avian influenza viruses from avian to human
نویسندگان
چکیده
منابع مشابه
Avian influenza viruses in mammals.
Highly pathogenic avian influenza viruses of subtype H5N1 are remarkable because of their expanding non-avian host range and wide tissue tropism. They have caused severe or fatal respiratory and extra-respiratory disease in seven naturally infected species of carnivore. However, they are not unique in their ability to cross the species barrier, to cause clinical disease and mortality, or to rep...
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1. Avian influenza (AI) viruses primarily circulate in wild waterfowl populations and are occasionally transmitted to domestic poultry flocks. However, the possible roles of other wildlife species, such as wild mammals, in AI virus ecology have not been adequately addressed. 2. Due to their habitat and behaviour, many wild mammals may be capable of transmitting pathogens among wild and domestic...
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While the basic principles of immunity to the influenza A viruses are probably similar for all vertebrates, detailed understanding is based largely on experiments in laboratory mice. Elements of the innate response limit early virus replication, although high pathogenicity strains can trigger effusive cytokine/chemokine production and lethal shock. Virus clearance is normally mediated via CD8+ ...
متن کاملAvian influenza viruses
Influenza viruses belong to the Orthomyxoviridae family, genus Orthomyxovirus, and are divided into three types – A, B, and C – based on the antigenic differences between their nucleoprotein and matrix proteins. Influenza A viruses are further subdivided into several subtypes. A most striking feature of influenza viruses is their ability to continually change their genetic structure – in partic...
متن کاملTenacity of avian influenza viruses.
The goal of this review is to provide an overview of existing research on the environmental tenacity of avian influenza (AI) viruses, to identify gaps in our current understanding, and discuss how this information relates to AI control, eradication, and prevention. We are just beginning to understand the environmental factors that affect infectivity and the extent of variation in environmental ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-48255-5